Infertility is not just a physical condition—it can also have spiritual roots. In Scripture, barrenness was often seen as a curse or an attack of the enemy designed to hinder God’s purposes. While medical conditions can explain some cases, there are also times when unseen spiritual forces are at work, opposing the fruitfulness God has promised His children.
God’s original design for humanity was multiplication and fruitfulness: “Be fruitful and multiply” (Genesis 1:28). Infertility contradicts this blessing, which is why many believers experience deep anguish when facing it. The enemy uses infertility to sow hopelessness, fear, and shame, but Christ came to redeem us from every curse.
The curse of infertility can stem from generational sin, spoken words, idolatry, or direct satanic attacks. However, through Christ’s sacrifice, the power of every curse is broken: “Christ redeemed us from the curse of the law by becoming a curse for us” (Galatians 3:13). Deliverance begins when we identify the curse, renounce it, and apply God’s promises in prayer.
This prayer will help you confront the spiritual roots of infertility, reject every lie of the enemy, and declare God’s Word over your life and family. As you pray, believe that the God who opened Sarah’s, Hannah’s, and Elizabeth’s womb is still performing miracles today. What He did for them, He will do for you—because He is faithful.
Powerful Prayer to Break the Curse of Infertility
Heavenly Father, I come before You in the mighty name of Jesus Christ, my Savior and Redeemer. I thank You because You are the Giver of life, the One who opens and no one can shut. Lord, You said in Your Word that none of Your children will be barren (Exodus 23:26). I hold firmly to Your promises today and refuse to accept infertility as my portion.
Father, I repent on behalf of myself and my bloodline for any sin, idolatry, covenant, or ungodly altar that may have opened the door to barrenness. I renounce every curse spoken over my womb, my seed, or my lineage. Let the blood of Jesus cleanse me from every iniquity and cancel every legal right of the enemy in my life.
In the authority of Jesus’ name, I break every generational curse of infertility and miscarriage. I command every evil covenant or agreement made knowingly or unknowingly to be destroyed by the power of the cross. I silence every evil voice declaring that I will not conceive or bring forth life. Those words fall to the ground and bear no fruit.
Lord, as You remembered Sarah, Rachel, Hannah, and Elizabeth, remember me today. I ask You to heal every physical condition in my body or my spouse’s body causing infertility. Touch our reproductive systems with Your resurrection power. Restore every organ to divine order and let Your healing flow.
I declare that my womb is blessed, fruitful, and productive. I cancel every medical report that contradicts Your Word. I reject fear, hopelessness, and delay. I speak life where there has been death, and I declare that my season of conception and fruitfulness has come.
Every demonic spirit of barrenness, be bound and cast out in Jesus’ name. Every altar crying against my fruitfulness, catch fire and be destroyed. Every satanic delay assigned against my destiny, be overturned by the power of the Holy Spirit.
Father, I ask You to surround me with peace and joy as I wait upon You. Let faith rise in my heart. Let every tear I have shed become a testimony of Your goodness. I trust You completely because You are faithful to perform Your Word.
I proclaim boldly: I will conceive, I will carry my baby to full term, and I will deliver safely. My household will rejoice because the Lord has done great things for me. Thank You, Father, for hearing my cry and granting me victory. I seal this prayer with the blood of Jesus. Amen.
10 Bible Verses on Breaking the Curse of Infertility
- Exodus 23:26 – “No one shall miscarry or be barren in your land; I will fulfill the number of your days.”
God promises fruitfulness to His people as part of His covenant. Infertility is not God’s will but an attack to be resisted. His Word declares that barrenness has no authority over those in covenant with Him. - Genesis 1:28 – “Be fruitful and multiply…”
This is God’s original blessing to humanity. Infertility contradicts this divine mandate, but through prayer and faith, believers can reclaim fruitfulness as their birthright. - Deuteronomy 7:14 – “You shall be blessed above all peoples; there shall not be male or female barren among you…”
This verse reaffirms God’s promise to bless His covenant people with fruitfulness, removing every curse of barrenness. - Psalm 113:9 – “He gives the barren woman a home, making her the joyous mother of children.”
God delights in turning barrenness into fruitfulness. He specializes in miracles where human strength fails. - 1 Samuel 1:27 – “For this child I prayed, and the LORD has granted me my petition…”
Hannah’s story proves persistent prayer breaks infertility. God answers those who cry out to Him with unwavering faith. - Isaiah 54:1 – “Sing, O barren one… for the children of the desolate one will be more than the children of her who is married.”
God promises abundance to those once barren. Joy and faith prepare the ground for breakthrough. - Luke 1:13 – “Your wife Elizabeth will bear you a son…”
Even in old age, God opened Elizabeth’s womb, proving nothing is impossible for Him. - Galatians 3:13 – “Christ redeemed us from the curse of the law…”
Jesus has broken every curse, including barrenness. Believers walk under His blessing, not generational bondage. - Hebrews 11:11 – “By faith Sarah… received power to conceive…”
Faith activates God’s promises. Even when Sarah’s body was old, faith brought fruitfulness. - Job 42:10,12 – “The LORD blessed the latter days of Job more than his beginning.”
God restores losses. Even after delay and affliction, He can multiply fruitfulness in His perfect timing.
Conclusion
Infertility is not your destiny—it is a temporary battle that God is able and willing to overcome. The same God who opened barren wombs throughout Scripture has not changed. He is still the Miracle Worker, and His Word cannot fail.
When you prayed this prayer, you confronted every curse and stronghold with the authority of Jesus Christ. Whether the root is physical, generational, or spiritual, God has already released His power to set you free. Even if symptoms remain, believe that the shift has already happened in the spirit realm. Faith is your weapon to hold onto the promise until it manifests.
Continue declaring God’s Word daily over your life and body. Reject fear and doubt, because these are tools of the enemy to weaken your faith. Surround yourself with godly counsel, prayer partners, and testimonies of others who have seen God’s faithfulness in similar battles. Your testimony is already written in heaven—you are simply walking it out on earth.
Do not let delay deceive you into thinking God has forgotten you. Like Sarah, Hannah, and Elizabeth, your story is being prepared for divine timing so that God will receive maximum glory. When the promise manifests, everyone will know it is the hand of God and not human effort.
Declare continually: “I am redeemed from every curse. My womb is blessed. I will conceive and bring forth children to the glory of God.”
Walk in joy and thanksgiving even before you see the result, because praise is proof of faith. Trust God completely, and do not reopen doors to fear or doubt. The curse of infertility is broken, and your season of fruitfulness has come.